Data were compared to transcriptomes of various other human leukemia models we had generated over the years, including CB CD34+ cells transduced with MLL-AF9 [32], FLT3-ITD [40], NUP98-HOXA9 [34], STAT5A [13,30,36,41] and KRASG12V [38] (Fig 1A, S1 Table). The gene discussed is KMT2A; the disease is leukemia.