APOL1 and Familial prostate cancer: It has also been reported that overexpressed APOL1 G0 (without G1 or G2 allele) causes cell death in multiple human cell lines, DLD-1 (colorectal cancer), HepG2 (liver cancer), MCF-7 (breast cancer), and LNCaP, PC3, and DU145 (prostate cancer) [20].