BRCA2 and breast carcinoma: From genetically derived cancers (estimated to account for some 5 to 10 % of all cancers) only about 1 % represents gastric carcinomas, 3–5 % for colorectal cancers, and about 8 % for breast cancers (breast cancer 1, early onset = BRCA1 or breast cancer 2, early onset = BRCA2) [17–19].