MMRN1 surfaces pre-treated with WT-VWF or VWF A1A2A3 (40 nM) supported the adhesion of resting platelets from controls and a type 3 VWD subject better than MMRN1 surfaces pretreated with BSA (p < 0.001, ▶Figure 5). This evidence concerns the gene VWF and von Willebrand disease 3.