PTEN and pachyonychia congenita: To benchmark this ratio score for the estimation of PTEN deletion in PC, we used 424 benign and malignant prostate formalin-fixed paraffin-embedded (FFPE) tissue samples, consisting of 339 radical prostatectomy (RPE) specimens, 28 castration resistant prostate cancers (CRPCs), 17 lymph node metastases, 11 distant metastases, and 29 benign prostatic hyperplasias (BPHs).