The 120 kDa protein present on the surface of B. dermatitidis has been proposed as a modulator of the immune response, since it is capable of inhibiting the inflammatory response through the production of TGF-β [29], contrary to the glycoprotein of the outer wall of the spherules of C. immitis and C. posadasii, which acts as an immunodominant antigen capable of inducing cellular and humoral responses during parasitic infections [30, 31]. P. brasiliensis GAPDH and a 30 kDa protein act as adhesins and have an important role in the interaction between the fungus and the host cells [26, 32]. Here, GAPDH is linked to parasitic infectious disease.