The SOI profile demonstrated variable serum levels of IL-2 in 52.3% of the patients, IL-12 in 85.2%, IFN-γ in 48.1%, IL-10 in 88.9%, and TNF-α in 100%; IL-4 was not detected, confirming both Th1 and Th2 cytokine profiles in the subclinical oligosymptomatic form of infection [5]. The gene discussed is IL4; the disease is infection.