Immunohistochemistry (IHC) analysis showed that the positive rate of C4BP was 87.4% (125/143), in which the strong positive rate of C4BP was 30.1% (43/143), in HCC tissues using tissue microarray containing 8 normal liver and 143 liver tumor cores (Figure 1A; Supplementary Table S1). Here, C4BPA is linked to hepatocellular carcinoma.