Interestingly, the difference was significant even when the median percentage of CD66b+CD33dimHLA-DR− cells within PBMCs of patients affected by HL [1.54 (0.28–26.34), p < 0.0001], and either indolent [2.15 (0.02–20.08), p < 0.0001] and aggressive B-cell NHL [2.96 (0.25–70.92), p < 0.0001] were compared to healthy donors (Figure 2). This evidence concerns the gene CEACAM8 and Hodgkins lymphoma.