Furthermore, the results from Kaplan-Meier survival curve analysis with log-rank significance test showed that the overall survival rate for NSCLC patients with negative expression of p-Mnk1 was significantly higher than those with positive p-Mnk1 expression (P = 0.011), as well as the overall survival rate for NSCLC patients with negative expression of p-eIF4E was better than these with positive p-eIF4E expression (P = 0.037) (Figure 1D). Here, EIF4E is linked to non-small cell lung carcinoma.