To determine the levels of PRSS8 in other cancers, we used 4 sets of TMAs that contained 72 pairs of esophageal cancers and their adjacent non-cancer tissues, 117 pairs of liver cancers and their adjacent non-cancer tissues, 46 pairs of prostate cancers and their adjacent adenoma or non-cancer tissues, and 75 pairs of breast cancers and their adjacent adenoma or non-cancer tissues, respectively. The gene discussed is PRSS8; the disease is Familial prostate cancer.