The results of ChIP-qPCR analysis showed that upstream regions of the mesenchymal marker genes Snail and Fibronectin, the PCa biomarker AMACR and AR precipitated with anti-Brachyury antibody showing that Brachyury directly binds to regulatory elements of these genes and suggests possibly regulation of those genes (Figure 4B). Here, AR is linked to posterior cortical atrophy.