TGFB1 and posterior cortical atrophy: We have previously shown by in silico analysis in PCa samples that Brachyury is associated with altered expression of genes involved in epithelial-to-mesenchymal transition (EMT), namely E and N-cadherin, Snail, TGF-β1, fibronectin, MMP14 and MMP24, and in stemness (CD44) [21].