In addition, many cytokines and chemokines are also found in RA patients’ synovial fluid, such as interleukin (IL)-1α, IL-3, IL-2, IL-4, IL-6, IL-8, IL-17, interferon (IFN) γ, tumor necrosis factor (TNF) β, transforming growth factor (TGF) β, granulocyte-macrophage colony-stimulating factor (GM-CSF) and macrophage inflammatory protein-3α (MIP-3α) (CCL20) [3,4]. The gene discussed is CSF2; the disease is rheumatoid arthritis.