All hematological parameters including Hb, HCT, MCV and MCH except MCHC were found to be significantly (P< 0.001, P< 0.001, P< 0.05, P< 0.05, respectively) lower than the controls, which are in accordance with the outcomes of the study conducted by Filiz Simsek et al.31.Total iron binding capacity (TIBC) was found to be significantly (P < 0.001) lower in beta-thalassemia patients than the controls. This evidence concerns the gene GSTM1 and Beta-thalassemia.