These findings are similar with the outcomes of other scientific studies.27,28 An increased potassium level occurs in patients with red blood cell (RBC) hemolysis, which may occur in stored blood that is transfused to the patient since potassium tends to leak out of the RBC in stored blood.27 An increased sodium level in beta-thalassemia patients may be due to renal damage resulting from iron overload.28 Higher level of serum AST, ALT and ALP in beta-thalassemia patients indicate an abnormal muscle and liver function. This evidence concerns the gene GPT and Tangier disease.