ADRA2A and cardiomyopathy: Our docking study reveals its molecular rationale as the binding affinity of both AAG drugs on D2, beta-2, GABA, ACE, Ca-channel, H2, and ADRA2A; most importantly trastuzumab has the highest binding affinity for NOS; this may be the probable cause that in trastuzumab treatment cardiomyopathy needs special attention.