The similar response to GnRH treatment between luteal and follicular cysts could be explained by the fact that follicular cysts may luteinize in response to GnRH treatment and cows with luteal cysts may not respond to GnRH treatment, and then cows with either luteal or follicular cysts will subsequently respond to PGF2α administered 10 days after GnRH treatment and this will result in a similar response to treatment. The gene discussed is GNRH1; the disease is Follicular Cyst.