The mean values of Hb (p<0.05), PCV (p<0.05), lymphocytes (p<0.01), MCV (p<0.01), MCH (p<0.01), and platelets (p<0.01) were significantly lower in liver cirrhosis group than control group, while TLC (p<0.01), neutrophils (p<0.01) and MCHC (p<0.01) were significantly higher than the control group. The gene discussed is GSTM1; the disease is cirrhosis of liver.