In addition, 5-FU could affect cell cycle, but UCA1 did not influence the cell cycle of CRC cells in this study, which was consistent with our previous work on miR-204-5p21, suggesting that UCA1 or miR-204-5p influences 5-FU sensitivity mainly by inducing apoptosis instead of cell cycle arrest. The gene discussed is UCA1; the disease is colorectal carcinoma.