To this end, we isolated cells derived from non-depleted (Dox−) FoxA1 or FoxA2 MCF7 and MDA231 tumours (control groups, GFP+/tRFP−), FoxA1- and FoxA2-depleted MCF7 and MDA231 tumours (GFP+/tRFP+), and the corresponding FoxA family-rescued tumours (GFP+/tRFP+), respectively (Fig. 2a). Here, FOXA1 is linked to neoplasm.