HUNK and neoplasm: Consistent with our previous findings, HUNK knockdown by shRNA (S1A Fig), as compared to JIMT-1 cells expressing control shRNA, impaired tumor growth by prompting a significant delay (18.4 days) in the median time for the tumors of HUNK shRNA expressing tumor cells reach a volume of ~600 mm3 (Fig 4A) and a significant reduction in tumor volume over time (S2A Fig).