FOXP3 and systemic lupus erythematosus: In addition, to estimate the effect of enriching the gut microbiota with strains able to increase the Treg subset, 5, 10 or 30% of SLE-M were replaced with the same amounts of Bifidobacterium bifidum LMG13195 (Bb), a strain known to induce Foxp3 expression23, 41, or with a mixture of two Clostridia strains (Cl) with a putative Treg-inducer effect (Ruminococcus obeum DSM25238 and Blautia coccoides DSM935)42, 43.