Triton X-100 soluble and insoluble brain fractions extracted from patients diagnosed as BIBD with chorea, aFTLD-U, or NIFID, as well as from a control patient were separated by 7.5 % sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotted with an anti-FUS antibody (Fig. 6). The gene discussed is FUS; the disease is Chorea.