Due to the fact that the STK31 gene exerts its important effects in various human cancers via its biological functions of increasing cell migration and invasiveness, suppressing cell apoptosis, promoting tumorigenicity and maintaining the undifferentiated state of cancer cells [12, 13], it has been speculated that the inhibition of HPV oncogene E7 in HPV-positive CCs contributes to CC therapy by inhibiting the tumor gene STK31 activities. Here, STK31 is linked to cancer.