FAN1 and Huntington disease: However, rs3512, the most significant individual SNP in this study, indexes the second significant chromosome 15 signal in GeM‐HD (p = 5.28 × 10–13, associated with 1.4 years later onset of HD), and is in the 3′UTR (untranslated region) of FAN1. Three SNPs (rs1037700, rs5893603, and rs16869352) were found to be in high LD (r2 > 0.8) in our sample with more significant SNPs from GeM‐HD.