In agreement, although both HCC70 and MCF-7 express wild-type BRCA1 and MDA-MB-468 has mutated BRCA1, MCF-7 is a luminal, while HCC70 and MDA-MB-468 are triple-negative breast cancer cell lines, which are more similar phenotypically to BRCA1-negative cells. Here, BRCA1 is linked to triple-negative breast carcinoma.