GSTO1 and coronary artery disorder: GSTO1 (glutathione S-transferase omega) related SNP in arsenic (As) metabolism exhibited nominally significant interactions with well-water “As” for connections with cardiovascular disease (CVD), coronary heart disease (CHD), or stroke [92]; in addition, GSTT1 polymorphisms serve as a potential genetic factor for arsenic-induced skin cancer [93].