KRAS and colorectal cancer: Although the G12V mutation is considered to be one of the most frequent KRAS codon 12 mutations in colorectal cancer patients—particularly in those with liver metastasis (ranging from 20.5% to 32.8%) [21,27]—the number of KRAS G12V-mutated samples in our population of study at La Paz University Hospital was very low (13 out of 554 total patients analyzed, representing 15.12% of total KRAS codon 12 mutations).