A study of 24 Chinese children by Hon et al. [28] showed that wrist activity during sleep was correlated with plasma concentrations of cutaneous T-cell attracting cytokine (CTACK), macrophage-derived chemokine (MDC), and thymus and activation regulated chemokine (TARC), but was not correlated with subjective pruritus or sleep loss. Here, CCL22 is linked to Pruritus.