The H3K27ac histone modification of PKN1 was located near the TSS in the lung adenocarcinoma cell lines (chr19:14544446–14544776 on hg19) (Fig 2(B)-A), while it was detected about 1 kb downstream of the TSS in NHLF (chr19: 14545611–14545886 and chr19:14546141–14546522 on hg19) (Fig 2(B)-B). This evidence concerns the gene PKN1 and lung adenocarcinoma.