PKN1 and lung adenocarcinoma: In order to explore the potential association between the aberrant gene expression described above and genetic polymorphisms, we examined the location of SNPs within the promoter regions (±1.5 kb from TSS) and gene bodies (exons and introns) of NUP210 and PKN1, which were aberrantly expressed in all of the 26 lung adenocarcinoma cell lines.