SLCO1B1 and Hyperbilirubinemia: The usual reported pattern of SMV hyperbilirubinemia was the mixed one (conjugated and unconjugated) and was possibly attributed to the inhibition of bilirubin hepatic transporters OATP1B1 and MRP2 by SMV resulting in the blockage of bilirubin clearance and drug-mediated reduction in hepatic uptake and/or conjugation of bilirubin, not associated with evidence of hepatotoxicity or hemolysis [11–13].