In contrast to the effects of BST‐2 on breast cancer cells, in HT1080 (human fibrosarcoma epithelial cell line) and MDCK (canine kidney cells) cells, overexpression of BST‐2 decreased cell growth and migration due to reduced matrix metalloproteinase 2 (MMP‐2) activity 130. The gene discussed is BST2; the disease is breast carcinoma.