Nine [breast invasive carcinoma, colon adenocarcinoma, HNSCC, clear cell renal cell carcinoma (RCC), papillary RCC, lung adenocarcinoma, lung squamous cell carcinoma, rectal adenocarcinoma, and stomach adenocarcinoma] of the 13 (69.2%) cancer types satisfied the 4 criteria for epigenetic silencing described in Section 2 for the NEIL1 gene, whereas none of the cancer types satisfied the criteria for the NEIL2 or NEIL3 gene (Table 2, Figures 2(a) and 2(b), Supplementary Figure S5, and Supplementary Table S6). This evidence concerns the gene NEIL2 and rectum adenocarcinoma.