Among the in vivo studies, an ethanol extract from Phoradendron serotinum leaves, tested from 1 to 10 mg/kg i.p., showed immunostimulatory effects, in a dose-dependent manner, by increasing the levels of IFN-γ, IL-2, and IL-6 in serum from C57BL/6 mice bearing TC-1 tumor [41]. This evidence concerns the gene IL2 and neoplasm.