IL22 and discoid lupus erythematosus: IL-22 serum concentration in DLE patients (median: 126.4 pg/mL, range: 85.8–955.5 pg/mL) was higher when compared to SCLE patients (median: 101.9 pg/mL, range: 34.4–249.9 pg/mL; P = 0.05).