AKT2 and infection: In C. elegans, it has been reported that the daf-2, age-1, akt-1, and akt-2 mutants were resistant to infection of Pseudomonas aeruginosa; however, the P. aeruginosa-infected daf-18 or daf-16 mutant showed similar lifespan to that of P. aeruginosa-infected wild-type nematodes25.