However, there were no statistically significant relationships between SHH expression and other clinicopathological variables such as age (P = 0.479), gender (P = 0.444), tumor location (P = 0.578), tumor size (P = 0.223), histological type (P = 0.357), degree of differentiation (P = 0.232), and Bormann classification (P = 0.924). The gene discussed is SHH; the disease is neoplasm.