The findings in this study are in contrast with the previously reported promising prognostic values for MMP-14 and MMP-2 in ovarian cancer [11, 19], but underline the later reports by Brun et al. [12] and Trudel et al. [13] This large retrospective cohort study with long-term follow-up has shown a correlation between epithelial MMP-14 and MMP-2 expression, and for both with stromal MMP-14 expression. This evidence concerns the gene MMP14 and ovarian cancer.