For example, Th9 cells express functional chemokine receptors CCR3, CCR6, and CXCR3 for the recruitment to disparate inflammatory sites; however, during allergic inflammation, Th9 cells preferentially use CCR3 and CCR6, not CXCR3; finally, Th9 homing to the central nervous system (CNS) during experimental autoimmune encephalomyelitis (EAE) involves CXCR3 and CCR6 but not CCR3 [78]. This evidence concerns the gene CCR3 and experimental autoimmune encephalomyelitis.