BRCA1 and BRCA2 mutations account for approximately 16% of the familial risk of breast cancer (Anglian Breast Cancer Study Group, 2000) and are also associated with increased risk of pancreatic, stomach, laryngeal, fallopian tube and prostate cancer (Venkitaraman, 2009; Roy et al, 2012). This evidence concerns the gene BRCA2 and breast carcinoma.