In addition to EBV, other viral causes of intrahepatic cholestasis include cytomegalovirus and viral hepatitis A, B, C and E. Acquired immune deficiency syndrome (AIDS) cholangiopathy is a syndrome of biliary obstruction resulting from infection-associated stricturing of the biliary tree, usually seen in patients with a CD4 count below 100/mm3. Here, CD4 is linked to hepatitis A virus infection.