The principal aim of this study is to examine associations of maternal pregnancy diabetes/glycosuria and pre-pregnancy BMI with offspring markers of NAFLD and liver pathology [ultrasound scan (USS) assessed fatty liver, estimated liver volume and stiffness (a marker of liver fibrosis) and fasting blood alanine amino transferase (ALT), aspartate amino transferase (AST), gamma- glutamyltransferase (GGT) and haptoglobin] in adolescence. The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.