Blood examination revealed hypoalbuminemia (serum albumin, 2.5 g/dL), renal insufficiency (serum creatinine, 0.92 mg/dL, Cys-C 1.69 mg/L, e-GFR, 63.1 mL/min/1.73 m2, hypocomplementemia (C3, 57 mg/dL; C4, 24 mg/dL; and CH50, 10.5 U/mL) and positive PR3-ANCA (19 U/mL; normal range 0-9 U/mL). The gene discussed is C3; the disease is Hypoalbuminemia.