Genotyping of 99 patients with T1D was performed: no DR3 and DR4 risk alleles were found in 22 (22.22 %) patients, DR3 alleles were present in 47 (47.48 %), DR4 alleles in 25 (25.25 %), and DR3/DR4 alleles in 5 (5.05 %) (Table 3). This evidence concerns the gene TNFRSF10A and type 1 diabetes mellitus.