Because previous studies have revealed that tumor-derived TGF-β1 mediates the conversion of CD4+Foxp3+ Tregs [34], we measured the percentage of CD4+CD25+Foxp3+ Tregs and CD103+CD4+Foxp3+ cells in lymphocytes from the spleens and lungs of tumor-bearing mice. This evidence concerns the gene ITGAE and neoplasm.