CCN2 and Alzheimer disease: Among the genes related to cell migration that were identified in PLum-AI cells, six genes (FLT1, PDGFRA, ITGA7, TGFBR3, MMP2, FMNL3) were upregulated and three genes (CTGF, THBS1, ST14) were downregulated, all compared to PLum-AD cells (Supplementary Table S3).