Furthermore, the HeLa-shSlug cells could xenograft the tumors earlier (11th day in the HeLa-shSlug cell group and 13th day in the HeLa-shcontrol group) and could develop much larger (Figure 3C, p < 0.05) and heavier tumors (Figure 3D, p < 0.01) than the HeLa-shcontrol cells, indicating that the knockdown of Slug in HeLa cells could enhance tumor formation in vivo. Here, SNAI2 is linked to neoplasm.