Our data show that the percentage of naïve CD4+ and CD8+ T cells in MDS is significantly lower than that in healthy controls [16.11 ± 6.56 vs. 24.11 ± 7.18 for CD4+ T cell (p < 0.001); 13.15 ± 5.67 vs. 23.51 ± 6.25 for CD8+ T cell (p < 0.001)] (Figure 2b and 2c). This evidence concerns the gene CD8A and myelodysplastic syndrome.