Through suppression of several oncogenes including p-AKT, EZH2, XIAP, CDK6, cyclin-D1 and cyclin-D2, overexpression of miR-340 inhibits cancer cell proliferation, migration and invasion, induces apoptosis and autophagy in glioblastoma and miR-340 is a marker for glioblastoma diagnosis and prognosis [30, 32, 33]. This evidence concerns the gene AKT1 and cancer.