While anemic subjects with complete G6PD deficiency are expected to be always classified as deficient regardless the normalization used, in women with intermediate G6PD phenotype the normalization of enzymatic activity in terms of IU/gHb might give higher normalized activity results as compared to the enzymatic activity expressed in terms of U/RBCs. The gene discussed is G6PD; the disease is hyperinsulinemic hypoglycemia, familial, 4.