A number of genes associated with PD risk have been found in both familial and sporadic Patients via genome-wide association studies (GWAS) and high throughput genotyping methods like next generation sequencing, including SNCA, LRRK2, PINK1, SLC45A3, ACMSD, HLA, GBA, RIT2, and CCDC624, 5. The gene discussed is ACMSD; the disease is Parkinson disease.